Question

Secretion of mineralocorticoids is under the influence of
a. FSH
b. TSH
c. ADH
d. ACTH

Answer 1

Hint: Mineralocorticoids are a type of corticosteroids, which eventually are a class of steroid hormones. Mineralocorticoids are formed in the adrenal cortex and alter salt and water balances (electrolyte balance and fluid balance). The major steroid with mineralocorticoid action is aldosterone.

Complete answer:
Cortisol said to have feeble mineralocorticoid activity which is of some prominence because cortisol is oozed very much more profusely than aldosterone.
Mineralocorticoids such as aldosterone, are steroid hormones formed from the adrenal cortex. They preserve electrolyte balance in the body by stimulating the absorption of sodium. Discharge of mineralocorticoids is stimulated by ACTH (Adrenocorticotropic hormone).

ACTH is discharged from the frontal lobe of the pituitary gland. It stimulates blood source to the adrenal cortex, enhances the concentration of cholesterol and steroids in the gland, and consequently, increases the yield of steroid hormones. The consequences of mineralocorticoids are facilitated by sluggish genomic mechanisms over nuclear receptors also by fast non-genomic mechanisms through membrane-linked receptors and signaling cascades.

Hence, the correct answer is option (D).

Additional information:
The kidneys secrete renin, which transforms angiotensinogen to angiotensin I. Angiotensin I is at that point cleaved by angiotensin-converting enzyme (ACE) to dynamic angiotensin II. Angiotensin II stimulates mineralocorticoid creation by the zona glomerulosa of the adrenals.

Note: Mineralocorticoid activity plays a significant role in renal sodium conservation. Reduced activity and renal resistance to mineralocorticoids are responsible for renal sodium-wastage. The most clinically applicable form of mineralocorticoid deficiency results from primary diseases of the adrenal cortex. Renal salt-wastage is a signal of Addison’s disease, in which patients may establish severe volume-depletion and cardiovascular failure.