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Name a peptide hormone that acts mainly on hepatocytes, adipocytes, and enhances cellular glucose uptake and utilization.
(A) Secretin
(B) Gastrin
(C) Insulin
(D) Glucagon

Answer
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Hint: In skeletal muscle and adipose tissue, insulin promotes membrane permeability of the glucose transporter GLUT4 from GLUT4 storehouse vesicles to the plasma membrane, hence promoting the uptake of glucose from the circulation.

Complete answer:
(A)Secretin
Secretin is discharged by endocrine cells of the duodenal wall in reaction to the existence of hydrochloric acid in chyme and causes the release of pancreatic juice from the pancreas.
(B)Gastrin
The enteroendocrine cells secrete gastrin which in roll promotes stomach-churning and causes more release of gastric juices.
(C)Insulin
Insulin supports to lower the blood glucose level by boosting the uptake of glucose by cells, specifically muscle cells, liver cells, and adipose tissue cells. Liver and muscle cells store glucose as glycogen. Glucose performs as an energy source for muscle compression and in adipose tissues, it provides glycerol for the building of fat.
(D)Glucagon
Glucagon hormone from the pancreas facilitates the liver to break down glycogen into glucose and deterioration of fat into glycerol and fatty acids in adipose tissues to assist as a substrate for glucose collection in liver cells.

Thus, the correct option is Insulin that is option C.

Note:
Insulin is a peptide hormone, which plays an important role in the principle of glucose homeostasis. Insulin acts primarily on hepatocytes and adipocytes (cells of adipose tissue) and increases cellular glucose taking and utilization