Question

MHC genes in humans are located on
A. chromosome 1
B. chromosome 2
C. chromosome 4
D. chromosome 6

Answer 1

Hint: Genes are contained in chromosomes, which are in the cell core. A chromosome contains hundreds to thousands of genes. Each typical human cell contains 23 sets of chromosomes, for a sum of 46 chromosomes. A few characteristics are brought about by mutated genes that are acquired or that are the consequence of new gene transformation.

Complete answer:
The major histocompatibility complex (MHC) is a huge locus of vertebrate DNA containing a lot of firmly connected polymorphic genes that code for cell surface proteins basic for the versatile safe framework. This locus got its name since it was found in the investigation of tissue similarity upon transplantation.

MHC atoms intercede connections of leukocytes, additionally called white platelets (WBCs), which are safe cells, with different leukocytes or with body cells. The MHC decides the similarity of benefactors for organs relocate, just as one's helplessness to an immune system infection by means of cross-responding vaccination.

In a cell, protein particles of the host's own aggregate or of other biologic elements are constantly combined and corrupted. Each MHC particle on the phone surface shows a little peptide, atomic division of a protein, called an epitope. The introduced self-antigens forestall a living being's invulnerable framework focusing on its own phones. The introduction of microbe determined proteins brings about the end of the tainted cell by the safe system. The qualities for the MHC complex are situated on chromosome 6 on account of people. On account of mice, these qualities are on chromosome 17.

So, the correct answer is “option D”

Note:
The MHC gene family is partitioned into three subgroups—class I, class II, and class III. Variety of antigen introduction, intervened by MHC classes I and II, is achieved in numerous ways:
> The MHC's hereditary encoding is polygenic,
> MHC genes are exceptionally polymorphic and have numerous variations,
> A few MHC genes are communicated from both acquired alleles (variations).
> MHC gene families are found in all vertebrates, however, they differ broadly.