Question

Match the following column and bring out the correct option of inhibitor and its effect.

Column 1	Column 2
a) Chloramphenicol	p) inhibits binding of aatRNA to ribosome
b) Erythromycin	q) inhibits interaction between tRNA and mRNA
c) Neomycin	r) inhibits initiation of translation
d) Streptomycin	s) inhibits peptidyl transferases activity
e) Tetracycline	t) inhibits translocation of mRNA over ribosome

A. a-p, b-q, c-r, d-t, e-s
B. a-r, b-p, c-t, d-s, e-q
C. a-q, b-r, c-s, d-p, e-t
D. a-s, b-t, c-q, d-r,e-p
E. a-t, b-s, c-p, d-q, e-r

Answer 1

Hint: 16 s RNA binds with the rRNA subunit and inhibition of the interaction between methionyl tRNA that is important for initiation of the protein synthesis. Antibiotics are also called streptomycin. The cause of death bacteria due to the absence of essential protein and lack of the protein presence in the inhibition initiation of the translocation.

Complete answer:
The 23 s RNA unit of the 50 s RNA and inhibits the transfer of the peptidyl transferases due to which the chain elongation of the protein present in the chloramphenicol is an bacteriostatic drug not take part in the prevention and transfer of the amino acid and inhibition of the further formation of the peptide bond chain. Erythromycin binds with the 50s RNA and transfers the amino acids in the protein synthesis. The attachment of the A site to move to the P site due to this A is permanently occupied in the prevention of the tRNA. Not chain elongation and tRNA attached with this and prevention of the bacteria from the synthesis of proteins required for its survival.

Therefore the correct option is (D).

Note: Tetracycline is also a type of an antibiotic and binds with the A site of the rRNA molecules and prevention of the binding of the aminoacyl tRNA. And attachment of the amino acid with the elongated peptide chain that binds with the A site. Tetracycline is used to prevent the infection that arises due to the respiratory tract, urinary system, intestines and pneumonia also.