Question

L-Dopa is used for the treatment of which disease?
A) AIDS
B) Parkinson's
C) Cancer
D) Heart attack

Answer 1

Hint: A disease is a specific aberrant condition that affects the structure or function of all or part of an organism without being caused by external damage. Medical disorders having particular indications and symptoms are commonly referred to as diseases.

Complete answer:
l-DOPA, also known as levodopa and l-3,4-dihydroxyphenylalanine, is an amino acid produced and utilized by humans, as well as certain animals and plants, as part of their regular biology. Humans, as well as certain other species that need l-DOPA in their biology, produce it from the amino acid l-tyrosine through biosynthesis.

Dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) are the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) are all precursors of l-DOPA. Furthermore, l-DOPA regulates the release of neurotrophic factors in the brain and CNS. Sinemet, Pharmacopeia, Atamet, and Stalevo are commercial names for l-DOPA, which may be produced and sold as a psychoactive medication with the INN levodopa. It's a medication that's used to treat Parkinson's disease and dopamine-responsive dystonia in patients.

The chirality of l-DOPA is opposite that of d-DOPA. The human body only generates one of these isomers, as it does with many other compounds (the l-DOPA form). The optical rotation of chiral thin-layer chromatography can be used to determine the enantiomeric purity of l-DOPA (chiral TLC).

Thus, L-Dopa is a substance that enters the central nervous system and is converted to dopamine by the enzyme DOPA decarboxylase. It is used to treat Parkinson's disease.

Thus the correct answer is option ‘B’.

Note: The conversion of l-DOPA to dopamine occurs outside of the central nervous system in humans. The peripheral nervous system's cells accomplish the same function. As a result, giving l-DOPA alone will enhance dopamine signalling in the peripheral nervous system. Excessive peripheral dopamine signalling is undesirable because it produces many of the negative side effects associated with L-DOPA alone.