Question

Lack of coordination and muscle twitching in disease takes place due to prion
A. Tetanus
B. Cancer
C. Kuru disease
D. Marasmus

Answer 1

Hint:
The word 'prion' refers to the abnormal, pathogenic agents that are transmissible and cause abnormal foldings of specific cellular proteins called prion proteins. Prion proteins are most abundantly found in the brain. The diseases due to these prion proteins are called prion diseases. This disease is a progressive neurodegenerative disorder that affects both animals and humans.

Complete step by step answer:
Clostridium tetani is the bacterium that causes tetanus. Tetanus does not spread from person to person and the spores of this bacteria are present almost everywhere such as in soil, dust and manure.
Prion proteins have two isoforms; cellular prion protein and pathogenic scrapie prion protein. Studies have shown that the cellular prion protein is involved in cancer biology. The tumour of the brain can irritate the neurons of the brain that causes muscle contraction, twitching and tingling, shallow breathing and loss of consciousness.
Kuru is a very rare and incurable disease and fatal neurodegenerative disorder, common among the fore people of Guinea. The kuru disease is caused due to the transmission of abnormally folded proteins called prions. The symptoms of this disease include a lack of coordination from neurodegeneration and muscle twitching.
Marasmus is a form of malnutrition i.e; protein-energy undernutrition and lack of macronutrients such as carbohydrates, proteins and fats. It is caused due to lack of calories. Respiratory infections, weight loss, stunted growth, diarrhoea and lower immunity are some symptoms of marasmus.
Thus, the correct answer is Kuru disease.

Option ‘C’ is correct

Note:
Kuru disease is fatal (any prion disease is fatal) and is found among the fore people of Guinea who practised cannibalism in which they ate the brains of dead people as a funeral ritual. This disease has a long incubation period. As of now, there is no known treatment for kuru.