Question

In tissues, amoebiasis is treated with
A. Tinidazole
B. Nitazoxanide
C. Metronidazole
D. Any of these

Answer 1

Hint:
In the treatment of symptomatic intestinal amoebiasis, tinidazole considerably outperformed metronidazole in terms of cure rates (p 0.01) and was also more tolerable. Although metronidazole is presently the recommended treatment for adults and children with invasive amoebiasis, it might not be enough to completely clear intestinal amoebic cysts.
Both tinidazole and metronidazole have great cure rates for the trichomoniasis they are used to treat. Tinidazole may also be useful for treating trichomoniasis that is resistant to metronidazole, according to certain in vitro studies and tiny case reports.
Tinidazole's impact varies depending on the patient's health and other factors. It typically takes two to seven days for the treatment to have its full effect on the microbes.

Complete answer:
The cornerstone of treatment for invasive amebiasis is metronidazole. The US Food and Drug Administration (FDA) has approved tinidazole for the treatment of extraintestinal or gastrointestinal amebiasis. Both invasive intestinal amoebiasis and the colonisation of the intestinal tract with E. histolytica can be successfully treated with nitazoxanide.
When certain protozoa produce diarrhoea, nitazoxanide is used as a treatment (tiny, one-celled animals). It is a member of the class of drugs known as antiprotozoals.
Extraintestinal amebiasis most frequently manifests as amebic liver abscesses. Additionally, necrotic lesions on the perianal skin and genitalia as well as pleuropulmonary and brain abscesses have been seen.
So, all of these options are used to treat amoebiasis in the tissue.

Option ‘D’ is correct

Note:
You can experience a metallic or bitter aftertaste in your mouth, nausea, upset stomach, diarrhoea, or vertigo. Inform your doctor or pharmacist as soon as possible if any of these side effects persist or get worse. Your urine's colour may darken as a result of this drug. A single oral dose of 1 ml/kg of secnidazole provided a much higher parasitological cure rate than two doses of tinidazole, according to this comparative investigation. A safe and efficient medication for the treatment of simple intestinal amebiasis is secnidazole.
Amebiasis can be cured with medication in a matter of weeks. However, if you continue to reside in or visit regions where amoebas are present, you can experience repeat bouts of amebiasis because treatment cannot prevent you from becoming infected once more.