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In batch fermentation
A) Substrates are added to the system all at once and run until the product is harvested
B) Nutrients are continuously fed into the reactor and the product is siphoned off during the run
C) New batches of microorganisms are screened for an increase in yield
D) Small scale production is used to synthesise the product

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Answer
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Hint: Fermentation is a biochemical mechanism that transforms carbohydrates into alcohols. It is a chemical mechanism in which molecules such as glucose are broken down anaerobically. More commonly, fermentation is the foaming that happens during the processing of wine and beer.

Complete answer:
Fermentation is a catalysed enzyme, a metabolic mechanism by which organisms convert starch or sugar to alcohol or anaerobic acid that releases energy. Fermentation science is called "zymology."
There are two types of fermentation process namely continuous and batch fermentation.

Batch fermentation is characterised as a closed system, whereby at time zero the substrate and the forming microorganism are added to the system and are not extracted until the fermentation is done. This represents the easiest and most widely used fermentation process for the creation of bacteriocins. Batch fermentation is a process in which the microorganism is inoculated to a defined volume of the medium. When the growth takes place, the nutrients that are absorbed and the growth product is also contained in the fermenter.

In batch fermentation, bulk processing is conducted as separate batches. In batch fermentation, the sterile nutrient medium is taken and inoculated with suitable microorganisms and is left for a period of time to allow the fermentor to develop. During the process, nothing is added or removed from the fermentor. In the end, the substance is removed.

Thus the correct answer is option ‘A’, substrates are added to the system all at once and run until the product is harvested.

Note: A microbial phase with a steady supply of culture medium through the reactor is continuous fermentation. In industrial applications, the amount of continuous fermentation is typically constant but can fluctuate in particular procedures, such as the handling of wastewater.