Question

If only one X chromosome is found in a female person, which of the following symptoms she will show?
A. Epicanthal skin fold
B. Webbing of neck
C. Small testis and absence of spermatogenesis
D. Presence of the simian crease on the palm

Answer 1

Hint: In the case where a female only possesses one X chromosome, it is clinically identified as Turner's syndrome. Turner's syndrome is a genetic condition that results in symptoms such as a webbed neck, low hairline, short stature, etc.

Complete answer: Turner syndrome is a genetic abnormality that occurs in females, wherein only one sex chromosome is present. This condition is also known as 45, X. This condition is caused by errors during fertilization, such as monosomy or abnormalities in the father’s sperm or mother’s egg. Turner syndrome is usually detected prenatally, but in some cases, symptoms are only visible during childbirth or teenage. Symptoms include a webbed neck, short stature, swollen palms, and infertility. People suffering from Turner syndrome cannot reproduce without fertility treatments and do not show proper sexual growth and require external hormone treatments. Webbed neck is characteristic of Turner syndrome.
a) Epicanthal skin fold is a condition where the upper eyelid covers the inner corner of the eye. This condition is widely seen in people of Asian heritage and is not characteristic of any genetic disorder.
b) Small testis and absence of spermatogenesis are characteristics of Del Castillo syndrome. This is a form of germ cell aplasia where there is no spermatogenesis in the testis. This cannot be the answer as the question pertains to a female subject.
Thus, the correct answer is option B.

Note: The simian crease is a condition where two palmar creases fuse and show a single crease that extends across the palm. This is often found in down syndrome, which is a genetic disorder where there is a deletion of the 21st chromosome and not the sex chromosome.