Question

Histamine, serotonin, and heparin are secreted by
A. Monocytes
B. Neutrophils
C. Eosinophils
D. Basophils

Answer 1

Hint: Histamine is an important neurotransmitter and is involved in various physiological processes, it acts during inflammatory responses. Heparin acts as an anticoagulant and prevents blood clotting. Serotonin has many physiological functions such as dilating capillaries, increasing vascular permeability, contraction of nonvascular smooth muscle.

Complete answer:
Histamine, serotonin, and heparin are secreted by the mast cells during inflammation and allergic reactions. A type of granular basophil cell consists of mast cells. Basophils are granulocytes that contain large cytoplasmic granules in the nucleus of the cell. Basophils store histamine which is a vasodilator also contains anticoagulant heparin and serotonin that induces the inflammation.
Monocytes secrete thrombospondin.
Neutrophils release cytokines.
Eosinophils inactivates the mediators released by mast cells.

Hence, the correct answer is option (D).

Additional information:
- Histamine is a chemical that is secreted by the stimulated cells that promote blood flow to
tissues.
- Heparin is an anticoagulant that prevents blood from clotting too quickly.
- The serotonin hormone stabilizes the feeling of well-being, mood and happiness. This hormone has an impact on the whole body. It helps in eating, sleeping, and digestion.
- Serotonin plays a role in the communication of nervous system cells and brain cells with each other.

Note: Basophils are the type of white blood cells. White blood cells contain granules in the cytoplasm which contains molecules heparin, histamine, and serotonin. These molecules are released during allergic reactions. Histamine is an allergic agent whereas heparin is anticoagulant. Motor activities of the body are affected by serotonin. Serotonin and histamine induce inflammation. Histamine is a chemical found in the cells of the body.