Question

‘Haemophilia’ disease is caused due to lack of
A. ADH
B. STH
C. AHF
D. ACTH

Answer 1

Hint: Haemophilia is a rare genetic inherited disorder that causes bleeding disorder due to failure in formation of clot as a result of mutation in the gene coding for clotting factor.

Complete Answer:
Let us analyse the options to find the correct answer.
Option A: ADH is an antidiuretic hormone which is secreted by hypothalamus of the brain. It is stored in the posterior pituitary gland and is responsible for regulating and balancing the amount of water in the blood. Therefore, this is the incorrect option.

Option B: STH is somatotropin which is produced by the anterior pituitary gland and is a growth hormone responsible for growth and development. They are usually given to individually suffering from dwarfism. Therefore, this is the incorrect option.

Option C: AHF, also called factor VIII, is a coagulating protein which is responsible for blood clotting and prevents bleeding problems in case of accidents or any disease. Therefore, this is the correct option.

Option D: ACTH is adrenocorticotropic hormone is a hormone which is synthesized in the pituitary gland and is responsible for managing stress. Therefore, this is the incorrect option.

Thus, the correct option is C) AHF.

Additional information: The gene responsible for coding of factor VIII or AHF is located on the X-chromosome.

Note: Alteration in the gene coding for factor VIII leads to this inherited bleeding disorder which prevents the formation of blood clots and blood flows easily through cuts and damages caused during an accident.