Question

Gout is caused due to the accumulation of uric acid. Why?

Answer 1

Hint: A gout is a form of arthritis that causes inflammation that begins suddenly, usually in one joint. Gouty arthritis is caused in a joint by the accumulation of needles-like uric acid crystals.- If gout is left untreated, kidney problems and tophi may cause permanent joint harm.

Complete step by step answer:
- Gout is caused in the bloodstream by too much uric acid and the accumulation of urate crystals in body tissues.
- Symptoms and signs of gout include nodules under the skin called tophi, redness of the joints, swollen joints, pain in the joints
- The most effective procedure for diagnosing gout is to drain fluid from an inflamed joint and to analyze urate crystals under a microscope.
- Uric acid is typically present in the body as a byproduct of the manner in which such proteins called purines are broken down by the body.
- Deposits of uric acid crystals in the joint cause joint inflammation, leading to discomfort, redness, heat, and swelling.
- Genetics, obesity, such drugs such as diuretics, and chronically reduced kidney function are the causes of elevated blood uric acid levels (hyperuricemia).
- The primary dietary aim of gout is to restrict the consumption of large levels of purine in foods.
- Ideally, only small quantities of those with moderate amounts of purine and you will have few to no foods that are rich in purine.
- Foods deemed to be rich in purine content include bacon, turkey, liver, and kidney of beef, sweetbread, and alcoholic drinks as well.
- Untreated gout for long periods can lead to joint damage and physical deformity.
- Kidney stones can be a symptom of gout since they can deposit uric acid crystals in the kidney and cause kidney stones.

Note:
- Joints in the lower extremities are mostly involved in gout.
- A tophus is a rough, uric acid nodule that is deposited under the skin.
- It implies that the body is significantly overloaded with uric acid when a tophus is present.