Question

At present, about ____ recombinant therapeutics have been approved for human use over the world. In India, ____ of these are presently being marketed.
A. 30, 12
B. 40, 20
C. 109, 32
D. 111, 9

Answer 1

Hint: For the treatment of many genetic disorders and other medical conditions biotechnology has developed many techniques for the treatment. The recombinant therapeutic proteins is one of them that modifies the proteins for the treatment of disease.

Complete Step by step answer: To solve this question, we have to know about recombinant therapeutic. The recombinant therapeutics are the therapeutic proteins that are formed from recombinant DNA technology. The recombinant hormone, tumor necrosis factor, interleukins, interferon, blood clotting factors, hematopoietic growth factors, enzymes, vaccines, monoclonal antibodies, and thrombolytic drugs are involved in the recombinant therapeutic process.
The recombinant proteins give a very huge success not just only in biomedical research but also in the treatment of many fetal diseases. The very first recombinant proteins were being applied as recombinant human insulin in 1982. There are more than 130 recombinant proteins that are under clinical trial after being approved by the US FDA. Till now, the recombinant therapeutic proteins have undergone three generations; the first generation includes the protein with its native structure, the second generation includes improved properties of protein mainly PK, specificity, efficacy, biodistribution, and minimal side effects. The third generation involves the recombinant proteins that have been improved for administration of novel routes with new formulation, high safety, and higher efficiency.
So, at present, about 30 recombinant therapeutics have been approved for human use over the world. In India, 12 of these are presently being marketed.

Thus, the correct answer is ‘A’. 30, 12.

Note: The recombinant therapeutic production is only possible due to recombinant DNA technology. In the recombinant DNA technology the target DNA is being altered for the proper function of the gene producing specific proteins.