
Assertion
The -As=As- linkage present in arsphenamine ( a sulfa drug) resembles the -N=N- linkage present in azo dyes.
Reason
The first antibacterial agent, prontosil resembles in structure to the compound salvarsan.
A.Both Assertion and reason are correct and Reason is the correct explanation for Assertion
B.Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion
C.Assertion is correct but Reason is incorrect
D.Both Assertion and Reason are incorrect.
Answer
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Hint: We are asked that Assertion ( The -As=As- linkage present in arsphenamine ( a sulfa drug) resemble the -N=N- linkage present in azo dyes) and the reason (The first antibacterial agent, prontosil resembles in structure to the compound salvarsan), both are correct or the reason is the correct explanation for the given assertion. First we will discuss the sulpha drug and then will see that which is the correct answer for the given question.
Complete step by step answer:
Sulpha drugs contain sulfonamide, a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulpha drugs. The original antibacterial sulpha drugs are synthetic (non antibiotic) antimicrobial agents that contain the sulfonamide group. Some sulfa drugs are also devoid of antibacterial activity, e.g. sultiame
So, the correct answer is Option B .
Additional Information:
Prontosil is the first synthetic drug used in the treatment of general bacterial infections in humans.
During discovery it was found that the first effective antibacterial agent, prontosil, which resembles in structure to the compound, was salvarsan. Soon it was found that in the body prontosil gets converted to a compound known as sulphanilamide, which is the real active compound. After that the sulpha drugs were discovered.
Note:
Antibacterial drugs are the drugs of materials that fight against pathogenic bacteria. Thus, by killing or reducing the metabolic activity of bacteria, so that their effect in the biological environments will be minimized.
Other than antibacterial drugs , antibiotics are also very effective against bacterial, fungal and parasitic infections. But, antibiotics are not so helpful against viral infections. The development of chemical synthesis has helped to produce the synthetic chemicals which act as an antimicrobial agent against the pathogenic effects of bacteria, fungus and parasites.
Complete step by step answer:
Sulpha drugs contain sulfonamide, a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulpha drugs. The original antibacterial sulpha drugs are synthetic (non antibiotic) antimicrobial agents that contain the sulfonamide group. Some sulfa drugs are also devoid of antibacterial activity, e.g. sultiame
So, the correct answer is Option B .
Additional Information:
Prontosil is the first synthetic drug used in the treatment of general bacterial infections in humans.
During discovery it was found that the first effective antibacterial agent, prontosil, which resembles in structure to the compound, was salvarsan. Soon it was found that in the body prontosil gets converted to a compound known as sulphanilamide, which is the real active compound. After that the sulpha drugs were discovered.
Note:
Antibacterial drugs are the drugs of materials that fight against pathogenic bacteria. Thus, by killing or reducing the metabolic activity of bacteria, so that their effect in the biological environments will be minimized.
Other than antibacterial drugs , antibiotics are also very effective against bacterial, fungal and parasitic infections. But, antibiotics are not so helpful against viral infections. The development of chemical synthesis has helped to produce the synthetic chemicals which act as an antimicrobial agent against the pathogenic effects of bacteria, fungus and parasites.
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