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Assertion: A negative catalyst retards the rate of chemical reaction.
Reason: Presence of negative catalysts boosted up the energy of activation.

Answer
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Hint: Catalysis is the addition of a catalyst to a chemical reaction to speed up the rate of the reaction. Catalysts are not consumed during the catalysed reaction, but they can be used again and again. In certain cases, only a small amount of catalyst is needed.

Complete answer:
Catalysis is the addition of a catalyst to a chemical reaction to speed up the rate of the reaction. Catalysts are not consumed during the catalysed reaction, but they can be used again and again. In certain cases, only a small amount of catalyst is needed.
Negative catalysts are catalysts that slow down or stop the rate of a reaction. The presence of foreign elements, which serve as negative catalysts, slows down chemical reactions.
It slows down the reaction by raising the activation energy barrier, which reduces the amount of reactant molecules that can be converted into products, slowing down the reaction.
The rate of a chemical reaction is slowed by a negative catalyst. The activity of a negative catalyst is related to the energy required for activation.
It's important to remember that enzyme inhibitors function as negative catalysts. They stick to the enzyme's allosteric site and slow down the reaction.

Hence, Both Assertion and Reason are correct and reason is the correct explanation for assertion.

Note:
Negative catalysts are catalysts that slow down or stop the rate of a reaction. The presence of foreign elements, which serve as negative catalysts, slows down chemical reactions. It slows down the reaction by raising the activation energy barrier, which reduces the amount of reactant molecules that can be converted into products, slowing down the reaction.