Question

What are three drugs that contain a pyrrole ring?

Answer 1

Hint: Pharmaceutical drugs are used for treatment and prevention of a wide variety of diseases. These drugs are made of molecules that contain an active site that can readily perform desired functions inside the human body. Many drugs utilize pyrrole rings containing structures as their active side.

Complete answer:
Pyrrole is a heterocyclic compound present in the form of an aromatic ring that contains nitrogen as one of the members. It is a five membered ring with two double bonds placed alternatively. Nitrogen itself is not part of the double bond but the lone pair on the nitrogen atom actively participates in the cyclic conjugation that takes place inside the ring.
The pyrrole ring is basic but due to the delocalization of the lone pair on nitrogen atoms, its basicity is somewhat reduced.
Pyrrole exists in the liquid state at room temperature in a colourless form but turns brownish with time as it is left to get exposed to the air. It has a distinctive and irritating odour and taste. The structure of a pyrrole ring is as follows:

The drugs that contain pyrrole are:
1.Atorvastatin (Lipitor) is a drug that is used to manage and control cholesterol levels in the body.
2.Tolmetin (Tolectin) is an anti-inflammatory drug that is used to treat swelling, pain and stiffness from arthritis.
3.Ketorolac (Toradol) is also an anti-inflammatory drug that is used to treat seasonal allergies, infections and eye pain.

Note:
A drug may contain pyrrole in its pure form or as a derivative. Some drugs utilize polymers of rings like the tetramer of pyrrole ring is actively used in many pharmaceutical drugs. Other heterocyclic aromatic drugs like furan are also used in making drugs.