What are the differences between an amine, amide and imine?
Answer
545.7k+ views
Hint: We know that to determine the major organic product formed from the reaction, we need to know what type of reactions are taking place. We can see that the reactant ketone is reacted with a primary amine and the product formed is further reacted with reducing agent lithium aluminum hydride.
Complete answer:
Amines are derivatives of \[N{{H}_{3}}.\] Amides are acid derivatives (or more rarely, anionic amines). Imines are nitrogen derivatives of carbonyl compounds. The difference between imine and amine is that imines are nitrogen derivatives of carbonyl compounds whereas amine is ammonia derivatives.
Organic amines, $NR_3$, are derivatives of ammonia, \[N{{H}_{3}}.\] Amide is a term that represents the acid derivative, \[RC\left( =O \right)N{{R}_{2}},\] or the conjugate bases of ammonia, for instance potassium amide, \[KN{{H}_{2}},\] which is unknown in aqueous solution, but known in liquid ammonia. Normally, the context will distinguish which amide is meant, and mostly in organic chemistry, the acid derivative (the former) is the one that is specified.
On the other hand, an imine is a carbonyl derivative, \[RC\left( =NR' \right)R\], formed by condensation of a carbonyl and an amine: \[RC\left( =O \right)R+{{H}_{2}}NR'\to RC\left( =NR' \right)R+{{H}_{2}}O\] the nitrogen has been substituted to the third degree, and most importantly, is surrounded by two secondary carbonyl groups. They are common in both synthetic and organic applications.
Note:
Remember that it should be noted that the reaction between the ketone and the primary amine is carried out in an acidic buffer; this is done so that the carboxyl \[C=O\] group can be activated and the dehydration can be facilitated without the nucleophile being inhibited.
Complete answer:
Amines are derivatives of \[N{{H}_{3}}.\] Amides are acid derivatives (or more rarely, anionic amines). Imines are nitrogen derivatives of carbonyl compounds. The difference between imine and amine is that imines are nitrogen derivatives of carbonyl compounds whereas amine is ammonia derivatives.
Organic amines, $NR_3$, are derivatives of ammonia, \[N{{H}_{3}}.\] Amide is a term that represents the acid derivative, \[RC\left( =O \right)N{{R}_{2}},\] or the conjugate bases of ammonia, for instance potassium amide, \[KN{{H}_{2}},\] which is unknown in aqueous solution, but known in liquid ammonia. Normally, the context will distinguish which amide is meant, and mostly in organic chemistry, the acid derivative (the former) is the one that is specified.
On the other hand, an imine is a carbonyl derivative, \[RC\left( =NR' \right)R\], formed by condensation of a carbonyl and an amine: \[RC\left( =O \right)R+{{H}_{2}}NR'\to RC\left( =NR' \right)R+{{H}_{2}}O\] the nitrogen has been substituted to the third degree, and most importantly, is surrounded by two secondary carbonyl groups. They are common in both synthetic and organic applications.
Note:
Remember that it should be noted that the reaction between the ketone and the primary amine is carried out in an acidic buffer; this is done so that the carboxyl \[C=O\] group can be activated and the dehydration can be facilitated without the nucleophile being inhibited.
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