Question

Acromegaly is due to hyposecretion of hormone from
A)Neurohypophysis
B)Adenohypophysis
C)Pars intermedialis
D)Cells of Leydig

Answer 1

Hint: It is an important organ of the endocrine system. It is mainly the glandular, anterior lobe that with the posterior lobe that is posterior pituitary or the Neurohypophysis makes the pituitary gland that is hypophysis.

Complete step by step answer:
-When the pituitary gland produces a large number of growth hormones during adulthood which led to the hormonal disorder known as acromegaly.
-Acromegaly causes bones of hands, feet, and face to increase in size. Usually, middle-aged adults are affected the most.
-When the pituitary gland overproduces growth hormone cause Acromegaly. From the anterior lobe of the pituitary gland, the growth hormone is secreted which is a part of the Adenohypophysis.
-In managing physical growth, the growth hormone plays a very important role. It is secreted in the bloodstream and triggers the production of a hormone called insulin-like growth factor-I.
-insulin-like growth factor-I stimulate the growth of bones and other tissue. Too much secretion of growth hormone release in the excessive amount of IGF-I that cause abnormal growth of soft tissues
and the skeleton is known as acromegaly.

So, the correct answer is, “Adenohypophysis”.

Additional information: Neurohypophysis - it is the posterior lobe of the hypophysis of the pituitary gland helps in storing and releasing oxytocin and vasopressin which is produced in the hypothalamus
Pars intermedialis - it is present as the boundary between the anterior and posterior lobe of the pituitary. It consists of basophils, chromophobes and colloid filled cysts cells. The remainder of Rathke's pouch is a cyst.
Cells of Leydig - it is present next to the seminiferous tubules in the testicles also known as interstitial cells of Leydig. In the presence of luteinizing hormones, they produce testosterone.
-These cells have a large nucleus an eosinophilic cytoplasm and numerous lipid-filled vesicles

Note:
-Non-cancerous tumor of the pituitary gland in most cases causes acromegaly. An excessive amount of GH hormone is secreted by the tumor which causes symptoms of acromegaly.
-The adenohypophysis secretes nine other hormones in which one of them is a growth hormone (GH) that promotes growth.