Question

Which statement is incorrect about \[{{G}_{0}}\]​ phase?
A. Mitosis occur after \[{{G}_{0}}\]phase
B. Biocatalysts can be used to speed up \[{{G}_{0}}\]phase
C. Cell volume keeps on increasing
D. Cell metabolism occurs continuous

Answer 1

Hint: Cells that have temporarily stopped dividing enter a phase called \[{{G}_{0}}\]​ phase, or it is said to have entered a state of quiescence. It is considered as a distinct quiescent stage that occurs outside the cell cycle or an extended \[{{G}_{1}}\] phase, where the cell is neither dividing nor preparing to divide.

Complete answer:
The cell division cycle or cell cycle consists of four distinct phases: Gap1 or \[{{G}_{1}}\]phase, synthesis phase or S phase, Gap2 or \[{{G}_{2}}\] phase or collectively known as inter-phase and M phase or mitosis. M phase or mitosis phase is composed of two tightly coupled processes: mitosis and cytokinesis. In mitosis, the cell's chromosomes are divided between two daughter cells. In cytokinesis, the cell's cytoplasm divides in half and forms distinct cells. Activation of each phase in the cell cycle is dependent on the proper completion and progression of the previous one. Cells that have either reversibly or temporarily stopped dividing are said to have entered a state of quiescence known as \[{{G}_{0}}\] phase.

Since, cells in \[{{G}_{0}}\]Phase are in a non-dividing phase outside the cell cycle, \[{{G}_{0}}\]Phase is sometimes referred to as post-mitotic state. Some types of cells, such as heart muscle cells and nerves, become postmitotic when they reach their maturity (i.e., when they are terminally differentiated) but these cells continue to perform their functions for the rest of that organism's life. Multinucleated muscle cells that do not undergo the process- cytokinesis are also considered to be in the \[{{G}_{0}}\] stage. On occasion, a distinction in terms is made between a post-mitotic and a \[{{G}_{0}}\] cell (examples are: neurons and heart muscle cells), which will never enter \[{{G}_{1}}\] phase, whereas other \[{{G}_{0}}\] cells may.

Hence, the correct answer is option (A).

Note: In organisms, although many cells in the \[{{G}_{0}}\] phase may die along with it, not all cells that enter the \[{{G}_{0}}\]phase are destined to die. This is simply a consequence of the cell lacking any stimulation to re-enter in the cell cycle.