Question

Which one is not an example for hydrolases?
a. Dehydrogenase
b. Protease
c. Amylase
d. Esterase
e. Sucrase

Answer 1

Hint: Hydrolase is a group of enzymes generally used as biochemical catalysts that use water to break up a chemical bond, that typically results in the division of a larger molecule into smaller molecules.

Complete answer:
Dehydrogenases catalyse dehydrogenation processes involving the addition or removal of electrons. The addition or removal of electrons will result in a reduction or oxidation of a substrate. Dehydrogenase is a type of oxidoreductase.

Some of the essential hydrolases include amylase, sucrase, lactase, maltase, protease, esterase, etc. Esterases split ester bonds in the lipids and phosphatases split phosphate groups away from molecules.

An example of essential esterase is acetylcholine esterase, which helps turn the neuron impulse to acetic acid after hydrolase breaks the acetylcholine into choline and acetic acid. Acetic acid is the main metabolite in the body and a critical agent for other reactions such as glycolysis. Lipases are hydrolyzing triglycerides.

Hence, the correct answer is option (A).

Additional information:
Hydrolase enzymes remain essential for the body as they have degradative properties. In lipids, lipases lead to the degradation of fats and lipoproteins and other big molecules into simpler molecules like fatty acids and glycerol. Fatty acids as well as other small molecules can be used for synthesis and energy.

In biochemistry, hydrolase would be an enzyme that catalyses a chemical bond hydrolysis. For eg, any enzyme which catalyses the following reaction is hydrolase:
${\text{A - B + }}{{\text{H}}_2}{\text{O}} \to {\text{A - OH + B - H}}$
Here, A–B shows a chemical bond that is of unspecified molecules.

Note: Systematic names of hydrolases are formulated as "substrate hydrolase." However, german names are usually given in the form of "substrates." For instance, nuclease is a hydrolase that breaks down nucleic acids.