Question

Which of the following statements is correct regarding the number of helper-T cells and the viral concentration in the blood?
A. As the number of HIV increases, so do the numbers of helper-T cells.
B. As the number of HIV increases, the number of helper-T cells decreases.
C. As the concentration of HIV decreases, the number of helper-T cells increases.
D. There is no relationship between the concentration of HIV and the number of helper-T cells.

Answer 1

Hint: Helper T-cells is a kind of immune cell that stimulates macrophages, killer T cells, and B cells to respond to the immune. A helper T cell is a kind of white blood cell and a kind of lymphocyte. It is also known as the CD4-positive T lymphocyte. Helper T cells are important for immune system function and activate after combating antigens from disease-causing microbes.
Complete step-by-step answer:
Helper T cells produce and secrete antibodies. Helper T cells are probably the most significant cells in adaptive immunity, when necessary for almost all adaptive immune responses. They not only activate B cells to secrete antibodies and macrophages to kill ingested microorganisms but also activate cytotoxic T cells to destroy infected target cells. As considerably proven in AIDS patients, without helper T cells we are unable to protect ourselves even against numerous microbes that are usually harmless. Generally, as the concentration of HIV rises, the number of helper T cells is destroyed which raises the number of cell counts to fall. After infection with the human immunodeficiency virus (HIV), the concentration of the virus in the individual's plasma increases. Several weeks later, the subsequent reduction in concentration was due to an HIV-specific immune response.
Therefore the correct answer is Option C.

Note: Helper T cells become activated through the interaction with antigen-presenting cells, like macrophages. Antigen-presenting cells ingest a microbe, partially destroy it, and export fragments of microorganisms—i.e., antigens—to the cell surface, where they are presented in collaboration with class II MHC molecules.