Question

Which of the following is employed as an antihistamine?
(A) Diphenyl hydra mine
(B) Norethindrone
(C) Omeprazole
(D)Chloramphenicol

Answer 1

Hint: Antihistamines are the class of drugs that act against histamine and neutralize the effect of histamines and prevent allergies. They block the action of histamine on the tissue. It relieves allergy symptoms. Histamine is responsible for causing allergic reactions within the body.

Complete step by step answer:
We know that antihistamines are drugs that counter the effect of histamines that are allergy-causing drugs. We will check one by one the action of these drugs and classify them as an antihistamine.
We have the first option as diphenyl hydra mine which is employed as an antihistamine. It prevents the interaction between the histamines and the receptors present in the stomach which releases less amount of acid. It is also known as Benadryl. So this is employed as an antihistamine. Hence this option is correct.
Norethindrone is a progestin medication used in many birth control pills to prevent pregnancy. It is also used to treat menstrual disorders, endometriosis. It is also used to treat abnormal vaginal bleeding. It binds to progesterone intracellular receptors in the reproductive system and the resultant activated complex interacts with specific DNA sites. Hence this option is incorrect.
Omeprazole is a benzimidazole with selective and irreversible proton pump activity. It reduces the amount of acid intake of the stomach. It is a widely used treatment for indigestion, heartburn, and acid reflux. It is an over the counter drug used to treat frequent heartburn. Hence this option is incorrect.
Chloramphenicol is a bacteriostatic antibiotic drug. It is used for the treatment of several bacterial infections. It is a man-made broad-spectrum antibiotic. Hence this option is also incorrect.
Therefore diphenyl hydra mine is employed as an antihistamine.

Hence, the correct answer is option A

Note: Diphenhydramine induces sleepiness, poor coordination, and an upset stomach as side effects. It is an anticholinergic drug and acts against acetylcholine activity. It is used in the treatment of cough and acts as a constituent in Benadryl.