Question

Which of the following diseases is not treated by inactivated 'Whole agent vaccine'?
A.Hepatitis A
B.Bubonic plague
C.Cholera
D.Typhoid

Answer 1

Hint: The inactivated whole agent vaccine uses the whole virus in the vaccine which is used for providing antigens and cures a particular disorder or infection.

Complete answer:
-The vaccine provides inactivated antigens to the body that activates the immune system to release antibodies for that antigen and this prevents that particular virus from entering the body furthermore.
-The whole agent vaccine developed for typhoid is known as the typhi vaccine which was made up of antigens that were inactivated with the help of acetone
-The whole agent vaccine was developed for many diseases but it didn't work for typhoid as it caused other symptoms like fever, body pain, inflammations, etc due to which it is no more used for the treatment of typhoid.

Option D: Typhoid cannot be cured by inactivated whole agent vaccines due to the harmful side effects and symptoms that appear due to that vaccine. Therefore, this is the correct option..

So, the correct option is option D.

Note: Nowadays treatment of typhoid is mostly done by using several effective antibiotics such as ofloxacin, ciprofloxacin, cefotaxime, etc. Typhoid is caused due to Salmonella Typhi and typhoid disease can be clinically confirmed with the help of the Widal test. The symptoms include fever, pinkish-red spots over the body, etc.