Question

Which of the following are not produced as transgenic animals?
A. Sheep and pig
B. Rat and rabbit
C. Dog and rabbit
D. Cow and fish

Answer 1

Hint: Organisms that have altered genomes are known as transgenic animals. These are the animals that are used to produce more protein in milk and meat, disease resistance, good quality of wool and improvement in genetic traits.

Complete step-by-step answer:
A transgenic animal is those whose genome has been altered by the transfer of a gene or genes from another species or breed. A transgenic animal is one that carries a foreign gene that has been inserted into its genome. Most transgenic organisms are generated in the laboratory for research purposes. Transgenic means that one or more DNA sequences from another species have been introduced by the artificial means. This results in the recipient animal giving birth to genetically modified offspring. The unexpected side effects including lameness, susceptibility to stress, and reduced fertility.
The most common transgenic animal used in research is the rat. Transgenic mice are also used to study different types of cancer. Transgenic pigs are being helpful as a source of organs for transplants, which if proven clinically safe could overcome some of the severe donor organ shortages. Other transgenic animals, such as pig, sheep and rats are also used, but their use in pharmaceutical research has so far been limited due to technical constraints. The first transgenic animal is Dolly which is the sheep . Transgenic rabbits are used to produce recombinant human ${C_{12}}$ esterase inhibitors. Some other transgenic animals that have been produced are cow, goat, fish etc. Rosie is the first transgenic cow.

Note: Mice are being used as models, for example, to study obesity, heart diseases, diabetes, arthritis, anxiety, ageing, ageing, Alzheimer’s and Parkinson’s diseases. Another advantage of mice is the fact that they have a short reproductive cycle.