Question

Which chromosome condition is Jacob syndrome?
(a)44+XO
(b)44+XXY
(c)44+XYY
(d)45+YY4

Answer 1

Hint: Males with jacob syndrome have 47 chromosomes because of the extra Y chromosome. Tall stature, gynecomastia, small testis, disability in learning, and, at times, infertility are some of the key features of this disease.

Complete answer:
-It is a rare chromosomal disorder present at birth that affects only males.
-It is not an inherited condition.
-The chromosome change usually occurs as a random event during the formation of sperm cells. Nondisjunction can occur during cell division.In such cases sperms may contain an extra Y chromosome in addition. It results in YY gamete from sperm.

Additional information:
-Since the Y chromosome is present, this condition affects only males.
-Individuals with XYY syndrome are not overly aggressive.
-They are not at an increased risk of any other mental disabilities.
-Common signs and symptoms of this syndrome include underweight, poor muscle tone, widely spaced eyes, learning disability, severe acne, hyperactivity, taller than average height, and so on.
- Diagnosis is done mainly during the prenatal stage through amniocentesis or chorionic villus sampling.
-Affected boys have delayed development of motor skills such as sitting and walking.

So, the correct answer is ‘44 autosomes + XYY’.

Note: Since it is impossible to correct every sex chromosome in our bodies, there is no treatment for XYY syndrome. Speech therapy, occupational therapy can help a person with XYY get through a delay in learning or development delays. It is found around 14.27 persons per 100,00 that may decrease the person’s lifespan.