
How have transgenic animals proved to be beneficial in the following application of transgenic?
A. Production of biological product
B. Chemical safety testing
Answer
561.6k+ views
Hint: Animals that have had their deoxyribonucleic acid manipulated to possess and categorical an additional (foreign) factor are called transgenic animals. The ordering of their animals has been modified and that they will carry genes from different species. samples of transgenic animals embrace rats, rabbits, pigs, sheep, cows, monkeys and fish though over ninety fifth transgenic animals are mice.
Complete answer:
Transgenic animals are terribly helpful as:
Some transgenic animals are made for specific economic attributes; different transgenic animals are made as illness models (animals genetically manipulated to exhibit illness symptoms so effective treatment are often studied).
They have found vital applications in terms of medicine:
Production of biological product
Medicines needed to treat bound human diseases will contain biological products, however such products are typically high-ticket to form.
Transgenic animals that turn out helpful biological products are often created by the introduction of the portion of deoxyribonucleic acid (or genes) that codes for a specific product like human macromolecule (a-1-antitrypsin) accustomed to treat respiratory disorder. Similar tries are being created for treatment of PKU (PKU) and fibrosis.
In 1997, the primary transgenic cow, Rosie, made human protein-enriched milk (2.4 grams per litre). The milk contained the human alpha-lactalbumin and was nutritionally a more balanced product for human babies than natural cow-milk.
Chemical safety testing
This is called toxicity/safety testing. The procedure is the same as that used for testing toxicity of medicine. Transgenic animals are created that carry genes that create them a lot more sensitive to hepatotoxic substances than non-transgenic animals.
They are then exposed to the hepatotoxic substances and also the effects studied. Toxicity testing in such animals can permit America to get leads in less time. Transgenic mice are being developed to be used in testing the security of vaccines before they're used on humans. Transgenic mice are being employed to check the security of the acute anterior poliomyelitis immunizing agent.
If thriving and located to be reliable, they might replace the employment of monkeys to check the security of batches of the immunizing agent.
Note: Transgenic animals are often specifically designed to permit the study of however genes are regulated, and the way they have an effect on the conventional functions of the body and its development, e.g., study of complicated factors concerned in growth like insulin-like protein.
Complete answer:
Transgenic animals are terribly helpful as:
Some transgenic animals are made for specific economic attributes; different transgenic animals are made as illness models (animals genetically manipulated to exhibit illness symptoms so effective treatment are often studied).
They have found vital applications in terms of medicine:
Production of biological product
Medicines needed to treat bound human diseases will contain biological products, however such products are typically high-ticket to form.
Transgenic animals that turn out helpful biological products are often created by the introduction of the portion of deoxyribonucleic acid (or genes) that codes for a specific product like human macromolecule (a-1-antitrypsin) accustomed to treat respiratory disorder. Similar tries are being created for treatment of PKU (PKU) and fibrosis.
In 1997, the primary transgenic cow, Rosie, made human protein-enriched milk (2.4 grams per litre). The milk contained the human alpha-lactalbumin and was nutritionally a more balanced product for human babies than natural cow-milk.
Chemical safety testing
This is called toxicity/safety testing. The procedure is the same as that used for testing toxicity of medicine. Transgenic animals are created that carry genes that create them a lot more sensitive to hepatotoxic substances than non-transgenic animals.
They are then exposed to the hepatotoxic substances and also the effects studied. Toxicity testing in such animals can permit America to get leads in less time. Transgenic mice are being developed to be used in testing the security of vaccines before they're used on humans. Transgenic mice are being employed to check the security of the acute anterior poliomyelitis immunizing agent.
If thriving and located to be reliable, they might replace the employment of monkeys to check the security of batches of the immunizing agent.
Note: Transgenic animals are often specifically designed to permit the study of however genes are regulated, and the way they have an effect on the conventional functions of the body and its development, e.g., study of complicated factors concerned in growth like insulin-like protein.
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