Question

: The hexose monophosphate shunt is also called as
A. EMP Pathway
B. HMP shunt
C. TCA pathway
D. None of these

Answer 1

Hint: Hexose monophosphate shunt is also called as pentose phosphate pathway, it is the metabolic pathway that is parallel to glycolysis, and in this pathway, NADPH and pentoses are formed, along with them a ribose-5-phosphate is also formed which is a precursor for the synthesis of nucleotides.

Complete answer:
Hexose monophosphate shunt is abbreviated as HMP shunt pathway.
It is an anabolic pathway.
It is important for erythrocytes and it occurs in the cytosol of the erythrocytes.
This HMP pathway has two phases, which include oxidative and non-oxidative phases.
In the oxidative phase of HMP shunt NADH are generated.
While in the non-oxidative pathway, they produce 5 carbon sugars.
The use of NADPH is, they use it in reductive biosynthesis reactions within the cell.
Ribose 5 phosphates are used for the production of nucleotides.
In the HMP shunt, erythrose-4-phosphate is also produced which is used for the synthesis of aromatic amino acids.
In the oxidative phase of the HMP shunt, glucose-6-phosphatase is converted to ribulose 5 phosphate, and the energy released in these reactions is used for reducing the NADP to NADPH.
In the non-oxidative pathway, this ribulose-5-phosphate which was produced undergoes several steps and produces ribose 5 phosphates used for the synthesis of nucleotides.
And the end products of this pathway are again used for glycolysis.

So, the correct answer is option B.

Note: In some people who are not having glucose-6-phosphate dehydrogenase enzyme, the HMP shunt is disrupted, and this is also associated with the resistance to the malarial parasite, plasmodium falciparum, among the individuals of Africa.