Question

The first clinical gene therapy was done for the treatment of ______.
(A) AIDS
(B) Cancer
(C) Cystic fibrosis
(D) SCID (Severe Combined Immuno Deficiency resulting from deficiency of ADA)

Answer 1

Hint: For the treatment of many genetic syndromes different techniques of recombinant DNA technology. Where new genes are constructed through recombinant DNA techniques. This technique includes PCR, blotting technique, gel electrophoresis, gene therapy, etc.

Complete answer:AIDS stands for acquired immunodeficiency syndrome are a chronic disease that are caused due to human immunodeficiency virus that harm the immune system in humans.
1. Now, cancer is a disease that is caused due to the abnormal growth of cells and spread throughout the body. This abnormal division results in tumor formation, there are two types of tumor; malignant and benign.
2. Cystic fibrosis is a hereditary disease that harms the lungs of the patient. The body produces sticky and thick mucus clog the lungs and creates pancreas obstruction.
3. SCID stands for Severe Combined Immune Deficiency resulting from deficiency of ADA. In this disease the function of T-cell and B-cell get harmed due to genetic mutation.

Additional information: Gene therapy is a therapeutic technique that uses genes to treat disease or to prevent it.
In the future, this technique could allow treating a disease by injecting a gene into another cell of a patient, rather than using drugs or surgery.
Researchers are exploring different gene therapy methods including: Replacing a defective gene with a balanced copy of the gene that causes illness. Knock out the defective gene that is incorrectly functioning, and development of a new gene into the body to help cure an illness.
The first authorized clinical gene therapy research was performed on September 14, 1990, under William French Anderson's guidance.
Four-year - old child has been treated for a genetic defect which left her with ADA-SCID, a severe immune system deficiency.

Hence, the correct option is D. SCID (Severe Combined Immune Deficiency resulting from deficiency of ADA).

Note: Gene therapy also involves the treatment of other diseases, like; cancer, cystic fibrosis, haemophilia, diabetes, and AIDS.
The defective genes or the defective cells that cause these diseases get altered with the help of gene therapy techniques.