Question

The blood does not clot inside the body because of
(a)Oxygenation
(b)Movement of blood
(c)Absence of active clotting factors in normal condition
(d)None of the above

Answer 1

Hint: Certain substances are responsible for the clotting of blood when there is any damage to the tissue. These substances remain in the inactive form within our circulation and are only activated by a mechanism known as cascade mechanism when there is any injury.

Complete answer:
For clotting of blood, the presence of certain factors like antithrombin III, heparin, protein C & S, thrombomodulin and alpha 2- macroglobulin inactive state undergoes series of reaction to final activation of enzyme thrombin is formed.zFew factor that can cause inactive the activated factors like vascular endothelium the activated factor and high blood flow prevents the accumulation of activation of activated clotting factor.

Additional Information: -Coagulation of blood is a process in which blood loses its fluidity and becomes a jelly-like mass a few minutes after it is shed out.
-The clotting mechanism occurs in three stages:
Formation of prothrombin activator
Conversion of prothrombin into thrombin
Conversion of fibrinogen into fibrin
-Coagulation can be initiated either by reactions occurring between components of the blood alone, the intrinsic pathway, or by the reaction which also involves tissue components termed the extrinsic pathway.

So, the correct answer is, ‘Absence of active clotting factors in normal condition.’

Note: -The extrinsic pathway formed from the injured tissues and formation of a prothrombin activator is initiated by the tissue thromboplastin.
-The intrinsic pathway is formed within the blood itself and the formation of the prothrombin activator is initiated by platelets.