Question

Sliding filament theory of muscle contraction was given by
A. Arnon and Hill
B. Huxley and Pullman
C. Huxley and Huxley
D. Pullman and Pullman
E. Pullman and Huxley

Answer 1

Hint: The sliding filament theory explains the mechanism of muscle contraction based on muscle proteins that slide past each other to generate movement.

Complete Answer:
- A. F. Huxley and H. E. Huxley observed changes in the sarcomeres as muscle tissue shortened.
- They observed that one zone of the repeated sarcomere arrangement, the "A band," remained relatively constant in length during contraction.
- The A band contains thick filaments of myosin, which suggested that the myosin filaments remained central and constant in length while other regions of the sarcomere shortened.
- The investigators noted that the "I band," rich in thin filaments made of actin, changed its length along with the sarcomere.
- These observations led them to propose the sliding filament theory, which states that the sliding of actin past myosin generates muscle tension.

So, the correct answer is ‘Huxley and Huxley'.

Note: Sliding filament theory explains the mechanism of muscle contraction.
It states that contraction of a muscle fiber takes place by the sliding of the thin filaments(actin) over the thick filaments(myosin).