Question

Rouleaux formation is related to which of the cell/tissue:
(a) RBC
(b) WBC
(c) Platelets
(d) Monocytes

Answer 1

Hint Rouleaux are clumps or aggregations of red blood cells that occur in vertebrates due to the discoid shape of the cells. The discoid RBCs' flat surface provides a huge surface area for them to make contact with and cling to one another, forming a rouleau.

Complete step by step answer:
The appearance of rouleaux can be induced intentionally by inadequate smear preparation or seeing the slide in a thicker area. An increase in cathodal proteins, such as immunoglobulins and fibrinogen, causes rouleaux formation when it is genuinely present.
They arise when plasma protein concentrations are high, and the ESR (erythrocyte sedimentation rate) increases as a result. This is a nonspecific sign of illness presence.
The existence of rouleaux, on the other hand, is a source of sickness since it restricts blood flow throughout the body because capillaries can only accept free-flowing, single, and independent red blood cells. The aggregations, sometimes known as "clumping," are caused by an allergic reaction to particular antibiotics rather than by disease.
Infections, multiple myeloma, Waldenström's macroglobulinemia, inflammatory and connective tissue disorders, and malignancies are all causes of rouleaux formation. It also happens in diabetes mellitus and is one of the causes of diabetic retinopathy's microvascular blockage.
Rouleaux formations are also used by spermatozoa to cooperate between genetically identical gametocytes in order to improve reproductive success by increasing motility and thus fertilisation capacity—for example, in the guinea pig.

A is the right answer. The stacking of four or more red blood cells is known as the Rouleaux formation.


Note: Capillaries can only accept free-flowing single and independent red blood cells, the presence of rouleaux is a cause of sickness because it restricts blood flow throughout the body. The aggregations, sometimes known as "clumping," are caused by an allergic reaction to particular antibiotics rather than by disease.