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Rh factor was discovered by
A.William Harvey
B.Landsteiner
C.Robert Hook
D.C. De Duve

Answer
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Hint:Several blood groups have been defined based on the antigens located on the surface of RBCs. A set of different genes determines each type of blood group. Rh factor is a type of blood group.

Complete answer:William Harvey was a physician who made many contributions in physiology and anatomy. He was best known and a famous physician to completely describe the systemic circulation and the other properties of blood being pumped by the heart to various parts of the body. Therefore, option A is wrong. Karl Landsteiner was an Austrian immunologist, biologist, and physician. In the year 1990, he discovered the main blood groups which are now considered as the modern system of classification of blood groups. He discovered the blood groups by identifying the presence of agglutinins in the blood. Later in the year 1937, along with Alexander S. Wiener, Landsteiner discovered the Rh factor. Therefore option B is correct. Robert Hook was the first person to visualize a microorganism using a microscope. He gave many contributions in the field of mechanics, physics, and gravitation. Therefore, option C is also incorrect. Christian De Duve was a cytologist and biologist. He won a Nobel Prize in Medicine for the discovery of two cell organelles, lysosomes and peroxisomes along with Albert Claude and George E. Palade in the year 1974. Therefore, option D is wrong.
So, option B is the correct option.

Note:There are two important blood grouping systems. They are the ABO blood group and Rh system. On chromosome 9, a set of three multiple alleles are present which is responsible for the four blood types. They are A, B, AB, and O groups. Only in humans and rhesus monkeys, Rh factor is found. Determination of the Rh blood group is based on at least 3 genes located on chromosome 1 each with two alleles.