Question

Restlessness, intolerance to temperature and increased metabolism is due to:
A) Thyrotoxicosis
B) ACTH deficiency
C) Pituitary deficiency
D) Calcitonin deficiency

Answer 1

Hint It is a state of having abnormally high levels of thyroid hormones that are circulating i.e., T3 and T4 in the body. This state is caused by excessive production of thyroid hormone. And this condition can be treated symptoms also include weight loss and rapid heartbeat.
Complete Step-by-step answer:
ACTH is the adrenocorticotropic hormone that is synthesized in the anterior lobe of the pituitary gland in response to corticotrophin-releasing hormone(CRH) released by the hypothalamus. ACTH stimulates the synthesis and secretion of steroid hormones called Corticosteroids from the adrenocortical cells of the adrenal cortex. So ACTH deficiency results in absence of production of ACTH which decreases the secretion of adrenal hormones i.e., Hypoadernalism.
Pituitary deficiency is also called hypopituitarism. It means when there is a short supply of one or more hormones released by the pituitary. It can affect growth, reproduction, blood pressure, and diabetes.
Calcitonin is a peptide hormone secreted by parafollicular cells of the thyroid gland that are distinct from the thyroid follicles. In case of high calcium levels in the blood, calcitonin is released by thyroid cells. And it decreases the concentration of calcium in plasma and decreases the calcium coming out of bones so it stimulates osteoblastic activity Calcitonin deficiency leads to osteopenia i.e., risk of bone degradation.
Thyrotoxicosis occurs due to increased levels of T3 and T4 in the body. Some of its symptoms are heat intolerance, anxiety, fatigue, muscle weakness, and irregular menses in females. And tachycardia, lid leg, etc.
Hence the correct answer is option A.
Note: The major hormone secreted by the thyroid gland is thyroxine or T4. It travels in the blood to carrier proteins. The thyroid also secrets a small amount of triiodothyronine or T3. And the carrier proteins have high affinity for T4 than T3.