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Prokaryotes differ from eukaryotes in the absence of
a. DNA
b. Basic proteins
c. Histones
d. Both B and C

Answer
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Hint: Prokaryotes are the microscopic structural organisms that have only a single cell. These organisms have neither a discrete nucleus with a membrane nor other specific organelles. The eukaryotes are the organisms that consist of the cells which are carrying their genetic material. It is called DNA which is in the form of chromosomes that are contained inside a distinct nucleus.

Complete answer:
The organisms of Prokaryotes differ from eukaryotes only in the absence of histones. The cells which are present in the prokaryotic organisms do not have intricate histone proteins as present in the cells of eukaryotes.

The prokaryotic organisms in the place of these histones have smaller, less complex, basic proteins called histone-like proteins which can be treated as the basic proteins which sustain the existence of the cell. One of the folding proteins which are profusely found in the nucleoid is HU.

In brief research we can say that the prokaryotes differ from the eukaryotes as they do not have a well-defined nucleus and well definite organelles. They defer since many prokaryotes are single in cells, however, on the other hand, eukaryotic organisms are single in cells and sometimes they are having multiple cells.

Hence, the correct answer is option (C).

Additional information:
The phylum of Prokaryotes includes microorganisms like bacteria and cyanobacteria. Even though they do not contain specific organelles they have a little amount of DNA and the basic proteins in them. The phylum of eukaryotes includes all living organisms other than the organism like bacteria and archaea.

Note: Thus, we can say the Prokaryotes and the eukaryotes are very different. The histones and other well-developed organs are present in eukaryotes. However, the Prokaryotes lack them. On the other hand, Prokaryotes have basic proteins and DNA. They help in the metabolism of Prokaryotes.