
Penicillin inhibits bacterial multiplication because it
A) Checks RNA synthesis
B) Checks DNA synthesis
C) Destroys chromatin
D) Inhibits cell wall formation
Answer
375.3k+ views
Hint: Penicillin is produced from Penicillin notatum. Penicillin is an antibiotic and is used in the treatment of throat infections, meningitis, syphilis, and various other infections. Hypersensitivity reactions, including skin rash, hives, swelling, anaphylaxis, or allergic shock are the chief side effects of penicillin.
Complete step-by-step answer:
Antibiotics are chemical substances or medicine, which are produced by some microbes that inhibit the growth of or kill or retard the growth of other ( disease-causing ) microbes. The first antibiotic discovered was penicillin. By inhibiting cell wall formation Penicillin inhibits bacterial growth, hence, killing the bacteria., Penicillin inhibits the formation of peptidoglycan cross-links in the bacterial cell wall and kills the bacteria.
Rifamycins inhibit bacterial RNA polymerase and are a family of antibiotics. Rifamycins bind to the bacterial DNA-dependent RNA polymerase, the enzyme that is responsible for the transcription of DNA into RNA.
Cyclin dependant kinases (cdk’s ) are required to activate DNA replication only once per cell cycle. The cyclin-dependent kinase inhibitors(CDK)inhibitors, flavopiridol, and roscovitine are in clinical trials as anticancer along with indisulam.
Therefore the correct answer is Option D.
Note: Checkpoint regulatory pathways are a major focus of attention because they are defective in cancer-predisposing human diseases. 7-hydroxystaurosporine(UCN-01) is a remarkably effective abrogator of G2 and S cell cycle checkpoint, particularly in p53 deficient cells. Penicillins are the most commonly used antibiotics in paediatrics and can be divided broadly into 4 different groups:
(1)natural penicillins,
(2) penicillinase-stable penicillins,
(3) aminopenicillins, and
(4) extended-spectrum penicillins.
Complete step-by-step answer:
Antibiotics are chemical substances or medicine, which are produced by some microbes that inhibit the growth of or kill or retard the growth of other ( disease-causing ) microbes. The first antibiotic discovered was penicillin. By inhibiting cell wall formation Penicillin inhibits bacterial growth, hence, killing the bacteria., Penicillin inhibits the formation of peptidoglycan cross-links in the bacterial cell wall and kills the bacteria.
Rifamycins inhibit bacterial RNA polymerase and are a family of antibiotics. Rifamycins bind to the bacterial DNA-dependent RNA polymerase, the enzyme that is responsible for the transcription of DNA into RNA.
Cyclin dependant kinases (cdk’s ) are required to activate DNA replication only once per cell cycle. The cyclin-dependent kinase inhibitors(CDK)inhibitors, flavopiridol, and roscovitine are in clinical trials as anticancer along with indisulam.
Therefore the correct answer is Option D.
Note: Checkpoint regulatory pathways are a major focus of attention because they are defective in cancer-predisposing human diseases. 7-hydroxystaurosporine(UCN-01) is a remarkably effective abrogator of G2 and S cell cycle checkpoint, particularly in p53 deficient cells. Penicillins are the most commonly used antibiotics in paediatrics and can be divided broadly into 4 different groups:
(1)natural penicillins,
(2) penicillinase-stable penicillins,
(3) aminopenicillins, and
(4) extended-spectrum penicillins.
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