Question

One group of neurotransmitter receptors is the metabotropic receptors. Which one of the following statements about metabotropic receptors is false?
A. Both muscarinic and p-adrenergic receptors are metabotropic receptors.
B. Metabotropic receptors are coupled with A proteins.
C. Metabotropic receptors can stimulate gene expression.
D. Muscarinic receptor bind with acetylcholine.

Answer 1

Hint:
The chemical messenger in the body is known as a neurotransmitter. Their main function is to transmit signals from nerve cells to target cells. Muscles, glands, etc are included in the target cell.

Complete answer:
Ionotropic and metabotropic are two types of membrane-bound receptors. These receptors are activated with the binding of neurotransmitters. Ionotropic is a group of transmembrane ion channels that open or close in response to binding with neurotransmitters. While metabolic receptors are a type of G-protein coupled receptor.
Metabotropic receptors are a subtype of membrane receptors and they do not form an ion channel pore. But they use G protein to activate a series of intercellular events. Glutamate receptors, epinephrine, neuropeptides, muscarinic acetylcholine receptors, P-adrenergic receptor, endocannabinoids, etc are some examples of metabotropic receptors.
The muscarinic receptor is activated by the molecule acetylcholine which allows any parasympathetic reactions in any organ. Group, I metabotropic glutamate receptor initiates a variety of signaling pathways. In addition to this, it can regulate gene expression in translation and transcription.
Hence the correct answer is Metabotropic receptors are coupled with A proteins. .

Option ‘B’ is correct

Note:
Neurotransmitter receptors are essential for mediating the effects of neurotransmitters in the brain and peripheral nervous system. Signaling through metabotropic receptors is much slower than signaling through ligand-activated ion channels.