
Mutation in how many genes causes the symptoms of cystic fibrosis?
Answer
525.3k+ views
Hint: Changes in the nature of the protein that generates the cystic fibrosis transmembrane conductance controller cause cystic fibrosis (CFTR). This protein is in charge of controlling the flow of salt and liquids in and out of cells throughout the body.
Complete answer:
Individuals with cystic fibrosis, also known as CF, experience a change in one or both of these qualities for cystic fibrosis symptoms to manifest.
All of our cells contain genetic information that gives the body coded instructions for creating proteins, which decide how the body looks, produces, and works. CF transporters are those who have one copy of the CFTR quality with a mutation and one copy of the normal CFTR quality. CF carriers who do not have the disease will pass on their damaged quality to their children.
Cystic fibrosis (CF) patients should undergo a transition in all CFTR qualities for the condition to manifest. This is because CF is a dormant disease, meaning that a person must inalienable two duplicates. A person who obtained one functioning duplicate of CFTR quality and performed a transformation on the second CFTR quality would be a disease carrier, but he or she would not be ill.
The third era in the image below contains two carriers, one who isn't a carrier, and one who has cystic fibrosis. The two carriers are the guardians of the third age, which means that for every child they have, each parent has a 50% chance of passing on the CF transition. As a consequence, the chance of a child conceived from these parents having CF is one fourth.
Note:
It's possible that the offspring of two CF carriers would be CF carriers as well. It's likely that neither of the kids, any of the children, or any of the people in a household of four will have CF. Even if not all of the other siblings are vectors or who have CF, each kid has the same risk of inheriting CFTR mutations from both parents. When a CF patient has children with a CF carrier, the children will either be CF carriers or suffer from the disease.
Complete answer:
Individuals with cystic fibrosis, also known as CF, experience a change in one or both of these qualities for cystic fibrosis symptoms to manifest.
All of our cells contain genetic information that gives the body coded instructions for creating proteins, which decide how the body looks, produces, and works. CF transporters are those who have one copy of the CFTR quality with a mutation and one copy of the normal CFTR quality. CF carriers who do not have the disease will pass on their damaged quality to their children.
Cystic fibrosis (CF) patients should undergo a transition in all CFTR qualities for the condition to manifest. This is because CF is a dormant disease, meaning that a person must inalienable two duplicates. A person who obtained one functioning duplicate of CFTR quality and performed a transformation on the second CFTR quality would be a disease carrier, but he or she would not be ill.
The third era in the image below contains two carriers, one who isn't a carrier, and one who has cystic fibrosis. The two carriers are the guardians of the third age, which means that for every child they have, each parent has a 50% chance of passing on the CF transition. As a consequence, the chance of a child conceived from these parents having CF is one fourth.
Note:
It's possible that the offspring of two CF carriers would be CF carriers as well. It's likely that neither of the kids, any of the children, or any of the people in a household of four will have CF. Even if not all of the other siblings are vectors or who have CF, each kid has the same risk of inheriting CFTR mutations from both parents. When a CF patient has children with a CF carrier, the children will either be CF carriers or suffer from the disease.
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