Question

Labile factor is associated with
A. Blood coagulation
B. Blood group
C. Blood immunity
D. Blood circulation

Answer 1

Hint: The labile factor also called Factor V is a protein that functions as a cofactor with other proteins in case of cuts or wounds. The labile factor originates in the liver and circulates in the blood along with blood plasma. A rare mild form of hemophilia is associated with labile factor deficiency.

Step by step answer:The labile factor or Factor V is also known as proaccelerin sometimes is an important cofactor required in the blood coagulation process. The labile factor is a protein that is not itself enzymatically active but acts as a cofactor for other proteins that are enzymatically active. It is one of the multicopper oxidases and is associated with chromosome 1. The labile factor originates in the liver and circulates in the blood having a half-life of 12 to 36 hours. Factor V is activated by thrombin. The labile factor further activates platelets in the blood at the site of cut or wound. As when the skin is ruptured the underlying blood vessels also get ruptured causing blood to flow. If the blood continues to flow the person will eventually die from excessive blood loss. To avoid this excessive blood loss a mechanism called blood clotting occurs in the blood with the help of platelet cells. These cells make the blood thick like jelly and form the clot.
Blood grouping refers to classifying blood based on the type of antibody and antigen present on the red blood cells of a person. Blood immunity is because of white blood cells, T-cells, B-cells, etc. that circulate in the blood. At last blood circulation is the regular transportation of blood throughout the body.
Thus, the correct answer is option A.

Note: Blood clotting is a type of positive feedback mechanism. Activation of one factor stimulates or activates the other factor. Various types of factors are involved in blood clotting. Venous thrombosis and mild forms of hemophilia are associated with deficiency of the labile factor.