Courses
Courses for Kids
Free study material
Offline Centres
More
Store Icon
Store
seo-qna
SearchIcon
banner

In which year, Khorana got the Nobel prize?
(a)1958
(b)1968
(c)1978
(d)1982

Answer
VerifiedVerified
485.7k+ views
Hint: Har Gobind Khorana won the Nobel prize in Physiology and medicine along with two other scientists Marshall W. Nirenberg and Robert W. Holley.

Complete answer:
In 1968, Har Gobind Khorana got the Nobel prize. He made an important contribution to genetic science by building different RNA chains with the help of enzymes. Along with Har Gobind Khorana, Marshall W. Nirenberg, and Robert W. Holley for their interpretation of genetics and its function in protein synthesis.

Additional Information: In 1968, M. Nirenberg, HG Khorana, and R. Holley shared the Nobel prize for physiology and medicine. Nirenberg and Khorana cracked the genetic code and Holley sequenced and deduced the structure of the first tRNA molecule.
Here's the brief explanation of Khorana's research:
Two alternating amino acids are produced by the RNA with two repeating units. This research combined with the Nirenberg and Leader experiment showed that UCU codes for serine and CUC codes for leucine. Three different strings of amino acids are produced by RNA with three repeating units. The RNA which has UAG, UAA, or UGA, produced only dipeptides and tripeptides and revealed that UAG, UAA, and UGA are stop codons.
The Nobel lecture was delivered on 12th December 1968.

Note: Har Govind Khorana was an organic chemist who specialized in the study of proteins and nucleic acids and was born in 1922 in Raipur. He confirmed Nirenberg's findings of the spiral staircase arrangement of nucleotides of the DNA and how it determines the chemical composition and function of a new cell. He added details about which serial combination of nucleotides from which specific amino acids. He also determined the transmission of nucleotide codes to the cell group called a codon and that some of the codons prompt the cell to start or stop the manufacture of proteins.