Question

Hybridoma cells are
A) Nerve cells
B) Hybrid cells resulting from myeloma cells and B-cells
C) Only cells having oncogenes
D) Products of spore formation in bacteria

Answer 1

Hint: Hybridoma is a hybrid cell used as the basis for the production of antibodies in large amounts for diagnostic or therapeutic use.This type of cells multiply indefinitely in laboratory and can be used to produce innumerable quantities of a specific antibody.The spleen cells are fused with cancerous white blood cells of humans to form the hybridoma cells which divide indefinitely.

Complete answer:
>Nerve cells are an active component of the nervous system.They can be regarded as the basis of the whole nervous system.They are naturally made in the body and not in the laboratory.The lifespan of a neuron or nerve cell is the same as the other cells in the body and they do not multiply indefinitely.Hence, it is clear that hybridoma are not nerve cells.
>Oncogene can be described as the gene with the potential of causing cancer.These genes are often mutated or expressed at high levels in tumour cells.Most normal cells will undergo a programmed form of cell death at a rapid stage (apoptosis) when the critical functions are altered and it ends in malfunctioning.
>Some bacteria such as Bacillus forms spores often referred to as endospores.These are basically the dormant groups of vegetative bacteria which are highly resistant to physical and chemical influences.>These are groups of organisms and are not related to hybridoma in any way.
>The hybridoma cells are composed when the spleen cells are fused with the cancerous cells of white blood cells of humans which are also known as myeloma.Hence, we can say that hybrid cells are a result of myeloma and B-cells.

Hence, the correct answer is option ‘B’.

Note:While attempting this question, one should not get confused between the second and third options.The third option talks about oncogenes and it is not only regarding the myeloma but the whole human body.In the centre of adaptive humoral immune system, the B-cells are located which creates Y-making proteins called ‘antibodies’ so that they can fight against bacteria and viruses.