
Human male sex hormone or androgen present in urine of males is
A. Testosterone
B. Androstenedione
C. Dehydroepiandrosterone
D. Androsterone
Answer
575.4k+ views
Hint: Androgens are the gathering of sex hormones that give men their 'male' attributes (all things considered called virilisation). The significant sex hormone in men is testosterone, which is delivered for the most part in the testicles.
Complete answer:
Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. It is a powerless androgen with a strength that is roughly 1/7 that of testosterone. Androsterone is a metabolite of testosterone and dihydrotestosterone (DHT). Furthermore, it tends to be changed over once again into DHT by means of 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, bypassing customary intermediates, for example, androstenedione and testosterone, and thusly, can be viewed as a metabolic moderate in its own right.
Androsterone is likewise known to be an inhibitory androstane neurosteroid, going about as a positive allosteric modulator of the GABAA receptor, and has anticonvulsant effects. The unnatural enantiomer of androsterone is more powerful as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the common form. Androsterone's 3β-isomer is epiandrosterone, and its \[5\]β-epimer is etiocholanolone. The 3β,5β-isomer is epietiocholanolone.
Androsterone has commonly been viewed as a dormant metabolite of testosterone, which when formed by glucuronidation and sulfation permits testosterone to be eliminated from the body, yet it is a frail neurosteroid that can cross into the mind and could have consequences for cerebrum work. Androsterone and its \[5\]β-isomer, etiocholanolone, are delivered in the body as metabolites of testosterone. Testosterone is changed over to 5α-dihydrotestosterone and \[5\]β-dihydrotestosterone by \[5\]α-reductase and \[5\]β-reductase, separately.
Note:
Androsterone was first detached in 1931, by Adolf Friedrich Johann Butenandt and Kurt Tscherning. They refined more than \[17,000\] litters (\[5\]\[3,700\] devil lady; \[4,500\] U.S. lady) of male pee, from which they got \[50\] milligrams (\[0.77\]gr) of glasslike androsterone, which was adequate to find that the synthetic recipe was fundamentally the same as estrone.
Complete answer:
Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. It is a powerless androgen with a strength that is roughly 1/7 that of testosterone. Androsterone is a metabolite of testosterone and dihydrotestosterone (DHT). Furthermore, it tends to be changed over once again into DHT by means of 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, bypassing customary intermediates, for example, androstenedione and testosterone, and thusly, can be viewed as a metabolic moderate in its own right.
Androsterone is likewise known to be an inhibitory androstane neurosteroid, going about as a positive allosteric modulator of the GABAA receptor, and has anticonvulsant effects. The unnatural enantiomer of androsterone is more powerful as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the common form. Androsterone's 3β-isomer is epiandrosterone, and its \[5\]β-epimer is etiocholanolone. The 3β,5β-isomer is epietiocholanolone.
Androsterone has commonly been viewed as a dormant metabolite of testosterone, which when formed by glucuronidation and sulfation permits testosterone to be eliminated from the body, yet it is a frail neurosteroid that can cross into the mind and could have consequences for cerebrum work. Androsterone and its \[5\]β-isomer, etiocholanolone, are delivered in the body as metabolites of testosterone. Testosterone is changed over to 5α-dihydrotestosterone and \[5\]β-dihydrotestosterone by \[5\]α-reductase and \[5\]β-reductase, separately.
Note:
Androsterone was first detached in 1931, by Adolf Friedrich Johann Butenandt and Kurt Tscherning. They refined more than \[17,000\] litters (\[5\]\[3,700\] devil lady; \[4,500\] U.S. lady) of male pee, from which they got \[50\] milligrams (\[0.77\]gr) of glasslike androsterone, which was adequate to find that the synthetic recipe was fundamentally the same as estrone.
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