Question

Give a schematic representation of gene therapy.

Answer 1

Hint: The first girl named Ashi Disiva in the year 1990 was the first patient to receive gene therapy for the severe combined immunodeficiency disease. After the therapy patient became healthy within the immune system that was able to fight off the most infectious.

Complete answer:
In gene therapy the replacement of the gene with the healthy one and deactivated the gene that is not functioning properly. In the gene therapy the new genes are introduced into the body to help to fight the disease. The effect of a normally functioning gene is enhanced with the help of gene therapy and activates the gene that was shut down during the fetal life.
There are gene therapy replacement, gene deactivation therapy, transgenes, and gene enhancement theory is the functional classification of the gene therapies. Somatic cells or germ line cells are the cell’s in which introduced the genes based on the type of cell. In the germ line gene therapy the normal version of the gene inserted into the green cells. In case of somatic cell Gene therapy the single defective cells taken out of an individual body and functional version of the genes introduced into the cell in the laboratory.

Note: Three types of gene introduced in the gene therapy ex vivo, in situ strategy and in vivo strategy. The gene therapy isolates the healthy gene along with the regulatory sequences to control its expression and incorporate the gene onto a vector and carrier as an expression cassette and deliver the vectors to the target cells. Some given examples of the vectors are retroviruses, adenovirus, adenovirus, and herpes simplex viruses.