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Give a brief account of the mechanism of synaptic transmission.

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Last updated date: 19th May 2024
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Answer
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Hint: Chemical transmission causes depolarization of the membrane and initiates an action potential. A faster method of nerve conduction than the chemical method of transmission is electrical transmission.

Complete answer:
A synapse is a junction between two neurons. It is present between the axon terminal of one neuron and the dendrite of the next neuron separated by a cleft.
There are two ways of synaptic transmission.
(1) Chemical transmission
(2) Electrical transmission
The mechanism of synaptic transmission at the electrical synapse:
-In this case, the presynaptic and postsynaptic membranes are in proximity.
-The impulse in the form of an electric current directly flows from the presynaptic neuron to the postsynaptic neuron.
-Transmission is faster than the chemical synapse.
The mechanism of synaptic transmission at the chemical synapse:
-the presynaptic and postsynaptic neurons are separated by the synaptic cleft.
-When an impulse arrives at the axon terminal, the calcium ions present in the synaptic cleft enter the synaptic knobs present at the axon terminals of the presynaptic neuron.
-The synaptic vesicles present in the synaptic knobs present in the presynaptic neuron move towards the plasma membrane and fuse with it.
-The vesicles release the neurotransmitter acetylcholine in the synaptic cleft. (Empty synaptic vesicles return to the cytoplasm of the presynaptic neuron where they are refilled.)

Note:
-The molecules of acetylcholine bind to the protein receptors present on the plasma membrane of the postsynaptic neurons.
-This binding opens the channels, and sodium ions enter the postsynaptic neuron, while potassium ions leave the postsynaptic membrane.
-This generates an action potential in the membrane of the postsynaptic neuron, and hence, the impulse is transmitted to the postsynaptic neuron.
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