Question

Enzyme taking part in converting dihydroxyacetone phosphate to glyceraldehyde phosphate belongs to the class of
A.Isomerases
B.Hydrolases
C.Ligases
D.Transferases

Answer 1

Hint: The conversion of dihydroxyacetone phosphate to glyceraldehyde phosphate takes place in glycolysis. Glycolysis is a widely known metabolic pathway that occurs in many organisms and is involved in the production of energy.

Complete answer:
Glycolysis consists of ten enzyme catalysed steps that are designated two different names- the preparatory phase which consumes ATP and pay off phase which produces ATP. The conversion of dihydroxyacetone phosphate to glyceraldehyde phosphate takes place during the preparatory phase which comprises several steps. The first step is the conversion of glucose to glucose-6-phosphate catalysed by the enzyme hexokinase which is a transferase class of enzyme. The second step is conversion of glucose-6-phosphate to fructose-6-phosphate by enzyme phosphoglucose isomerase which is an isomerase class of enzyme. This is followed by conversion of fructose-6-phosphate to fructose 1,6-bisphosphate by the enzyme phosphofructokinase which is a transferase. Fructose-1,6-bisphosphate is converted to dihydroxyacetone phosphate and glyceraldehyde phosphate by the enzyme fructose bisphosphate aldolase which belongs to the lyase class of enzyme. Finally the dihydroxyacetone phosphate is converted to glyceraldehyde phosphate by the enzyme triosephosphate isomerase which belongs to the isomerase class of enzyme.

Hence, the correct answer is option (A)

Note: The pay off phase also comprises several steps. The glyceraldehyde phosphate is converted to bisphosphoglycerate, which is converted to 3-phosphoglycerte. The 3-phosphoglycerate is converted to 2-phosphoglycerate. The 2-phosphoglycerate is converted to phosphoenolpyruvate which is then finally converted to pyruvate.