Question

During DNA replication, Okazaki fragments are used to elongate.
A. The lagging strand away from the replication fork
B. The leading strand towards replication fork
C. The lagging strand towards replication fork
D. The leading strand away from replication fork

Answer 1

Hint: DNA: It is deoxyribonucleic acid. It is composed of two polynucleotide chains that coils together to form a double helical structure. It is present inside the nucleus of the living cell, but a small amount of DNA is found in mitochondria also. DNA helps in replication, encoding information, mutation and recombination and gene expression.

Complete answer:
- DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.
- The most important part of biological inheritance that occurs in living organisms is DNA replication.
- DNA replication is the process in which the DNA is replicated and two copies are synthesized.
- It involves the formation of a replication fork.
- Template strand is the two strands of the DNA helix which are separate and the new strands are formed on the original strands.
- The strand which is synthesized in 3'-5' direction is the leading strand
- The strand which is synthesized in the opposite direction is the lagging strand which contains the Okazaki fragments.
- This strand is synthesized away from the replication fork.

Hence, the correct answer is option (A).

Note: DNA strands are polymers of deoxynucleoside monophosphate that are joined together by phosphodiester bonds. Chromosomes of many organisms are made up of two DNA strands:
- One strand is oriented in 5-3 direction which represents the carbon atom.
- and second is Complementary chain which is in 3-5 direction and these two DNA strands are held together by hydrogen bonds.