Question

Dopamine neurons are connected with syndrome
A) Horton’s syndrome
B) Parkinsonism
C) Schizophrenia
D) Both B and C

Answer 1

Hint: It is a common neurological disorder that is characterized by degeneration of dopamine neurons in the substantia nigra. It is described as the motor disease and it also produces behavioral and cognitive symptoms.

Complete Answer:
- Dopamine dysregulation syndrome can be observed in individuals who have taken dopamine for an extended period of time.
- Dopamine neurons are connected with Parkinsonism syndrome. Parkinson or paralysis is a neurological disorder that affects movement control.
- Dopamine neurons of substantia nigra degenerate and as a result, the amount of DA is available for neurotransmission in the corpus striatum is lowered. The symptoms include gradual slowness of spontaneous movement, loss of postural reflexes or in other words, motor coordination and poor imbalance.

Thus, the correct answer is option B i.e, Parkinsonism.

Additional information: Horton’s syndrome is a very painful and rare type of headache. It is also called cluster headache.
- It strikes quickly without any warning and causes shooting pain behind and around an eye. Schizophrenia is a disorder that affects the ability of a person to feel, think and behave clearly. It is a serious mental disorder.
- The factors like genetic psychological, physical and environmental factors are responsible for developing this condition.

Note: Parkinson disorder produces cognitive and behavioral symptoms which includes motor coordination and poor imbalance. The prevention is possible by the low dose of dopamine to individuals at risk and also L-Dopa can also reduce risk of this syndrome.