Question

Who discovered DNA polymerase
A)Okazaki
B)Kornberg
C)Meselson and Stahl
D)Watson and Crick

Answer 1

Hint: It was discovered by the American botanist who was born in 1918, March 3. He also got the Nobel Prize in Physiology and medicine in 1959. He discovered the enzyme DNA polymerase from potatoes.

Complete answer:
Arthur Kornberg, spent his 60 years during his research career and made an outstanding contribution to molecular biology. The enzyme that assembles DNA from its component is known as the DNA polymerase and Arthur Kornberg was the first to isolate this DNA polymerase. He was also the first person to synthesize DNA in a test tube and for this, he earned a Nobel prize in 1959.

Additional Information: The function of DNA polymerase
DNA from deoxyribonucleotides is synthesized by DNA polymerase. Nucleotides paired with the original DNA molecule with the bases on each strand to create DNA copies.
-Cytosine is paired with the guanine and thymine is paired with the adenine.
-The DNA polymerase can only add nucleotides to a pre-existing 3'-OH group, they are not able to form new chains.
-This shows that DNA polymerase requires a primer to add the first nucleotides.
-Primers can have either RNA or DNA bases they don't have both. The first two bases are always RNA when DNA is replicated.
-The Primase synthesized DNA molecule and helicase, as well as topoisomerase II, unwind them to form double-strand DNA from a single strand DNA
Structure of DNA polymerase
Most of the DNA polymerase resembles the structure of the hand and holds two active sites. Nucleotides are added at the insertion site and when a new base perform it Migrates to the post-insertion site
So, the correct answer is ‘Arthur Kornberg’.

Note: -The major function of the DNA polymerase is synthesized the DNA and do it by adding the nucleotides at the 3’-OH group of the growing DNA strand.
-For the first time, DNA polymerase is purified and characterized from the E-coli by Arthur Kornberg.