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Difference between crystalloid and colloid is of:
A) Particle size
B) Chemical composition
C) Ionic character
D) Solubility

Answer
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Hint:Both crystalloid and colloid can be easily soluble in water.The particles size of crystalloid are generally smaller, in some cases the particles size are even smaller than the one-nano-meter, whereas, in Colloids the particles size are quite larger, in some cases the particles sizes vary from 1-200 nano-meter.

 Complete step by step answer:
As per question,We have to differentiate the Crystalloid and Colloid.As we know that,
Colloids are homogeneous as well as non-crystalline substances, which are made up of large particles/ molecules or made up of ultramicroscopic particles. In colloids normally one substance is dispersed under another substance.
Some examples of such solutions are gels, emulsions.
The particles of colloids are usually cannot be separated out by any of the normal process.Colloids come under category of non-aqueous solutions.While,In Crystalloid solution,Normally, Crystalloids are those substances, which can be easily crystalized from their aqueous form.The particle size of such elements is very small.Crystalloid solutions are come under the category of homogenous solutions,
They are easily soluble in water, therefore they come under the category of aqueous solution.
Some examples of such elements are, salt, sugar etc.
Hence, From the above stated points, we can conclude that,Both Crystalloid and Colloid come under the category of Homogenous solution.Both are aqueous in nature.Chemical composition of both Crystalloid and Colloid are quite similar.
Hence, on the basis of particle size, both crystalloid and colloid can be easily differentiated.
Hence, Option A will be the right choice of this question.

Additional Information:
The life span of Crystalloids is more than the life span of Colloids.Colloids are needed to be stored under refrigeration, while Crystalloids are normally put under room temperature.Crystalloids are used as a source of electrolytes for the human body, but we cannot use Colloids as a source of electrolytes for the human body.

Note:As, both Crystalloids and Colloids are homogeneous type of solutions, so we can easily conclude that the ionic structure of both will be similar.The particles size of Crystalloid is much smaller than the particle size of Colloids.
Colloids cannot pass through the plasma membrane of cell, but Crystalloid can easily pass through the plasma membrane of cell.