Question

What is the difference between a haplotype and a genotype?

Answer 1

Hint: Haplotypes are a collection of genetic variants found on the same DNA molecule. Each haplotype has two sequences for each gene in the diploid genome. Each of a gene's two sequences could determine different biological activities for its gene products due to genetic diversity.

Complete solution:-
These are two concepts that are intertwined.
1. A haplotype is a collection of DNA variants that are frequently passed down in families. These haplotypes are found on a single chromosome. The alleles that make up a haplotype might be found all around the chromosome, yet they are all inherited together.

2. A genotype can refer to a single attribute or a group of traits inherited from one parent. The genotype is the set of genes found at a specific location.

3. Thus, while the genetic material in a haplotype can be distributed over several loci or places on the chromosome, the genetic material in a genotype is concentrated at a single locus.

4. A haplotype is a set of genes in an organism that were all inherited from the same parent. The word "haplotype" comes from the words "haploid," which refers to cells with just one set of chromosomes, and "genotype," which refers to an organism's genetic composition.

The term haplotype refers to a haploid genotype. It refers to a set of specific alleles found in a group of closely connected genes. The cluster of HLA alleles in the major histocompatibility complex is a famous example (MHC). Even between-gene regions of DNA can be found as distinct haplotypes.

Note:-
Haplotypes are allelic combinations of several markers found on a single chromosome of a single person. When haplotypes are transmitted down through generations, recombination will split them up. After many generations, the amount of ancestral haplotypes will have shrunk significantly.