Question

Can humans get scrapie?

Answer 1

Hint: Infectious protein particles best known as 'Prions' are referred to as a virus-like agent associated with such illnesses. This is a disease that follows a gradual, progressive path lasting months to years after a prolonged latency time, mostly affects the central nervous system, and progresses to death in most cases, and mostly occurs in sheep.

Complete answer:
-Scrapie is a dangerous disease that mostly occurs in sheep and rarely occurs in humans or completely absent in humans. In this disease the sheep start to work slow, their body starts to get degenerate, and slow. It was found to be caused by prions and the cases of its transmission in humans are not found yet.
-It can be transmitted in other sheep via various body fluids or through some cuts in their skin. The problem caused by this disease mainly occurs in the lymphatic system of the body.
-Prions are "infectious" misfolded proteins since they can induce misfolding in other previously normal proteins, but they do not contain DNA or RNA, so they cannot be labeled as viruses. They speculated that small virus particles, which they called virions, were to blame until scientists understood the cause of spongiform encephalopathy. The word virions were discarded and these particles were called prions after it was discovered that prions were the real cause of TSEs and that prions contained no nucleic acid.

Additional information:
-Prions are infectious particles of protein that function as a pathogen that causes the human neurodegenerative disorder. They lack genetic material and multiply to refold into a shape called PrP scrapie by stimulating normal cellular prion protein. It is a malformed protein, so it does not replicate and is also known as a slow virus.
-Transmissible spongiform encephalopathies (TSEs), like Creutzfeldt-Jakob disease, kuru, sheep scrapie, and cattle bovine spongiform encephalopathy (BSE), were previously known as slow viral diseases. TSEs are more accurately known as prion diseases, however.

Note:
Prions are so-called because only protein tends to contain them. In any prion particle examined, no proof of nucleic acid has been detected. Protein-depleting treatments, such as denaturation, eliminate prion infectivity, but nucleic acid-depleting treatments, such as UV radiation, do not kill prion infectivity.